This test is used to evaluate levels of coagulant factor VIII. A deficiency in Factor VIII is known as hemophilia A. It is the most common of the hereditary bleeding disorders. Elevated levels are associated with the development of the geriatric syndrome of frailty. Fasting is not required for this test. Take all medications as prescribed.

This test is intended for use in screening individuals who may be at risk for heart disease and stroke. Homocysteine is an independent risk factor for coronary heart disease. High blood levels may directly damage the delicate endothelial cells that line the inside of arteries and result in vascular inflammation, blood clot formation, and arterial plaque rupture. An 8 to 12 hour fast is required for this blood test. However, drink plenty of water and take medications as prescribed.